Perimenopause brings change, but you don’t have to struggle with uncomfortable symptoms. Hot flashes, mood swings, and sleep problems can disrupt daily life, but effective treatments are available. From hormone therapy to natural approaches, there are ways to feel more like yourself again. Exploring your options is the first step to taking control.
Key Takeaways
- Hormone Therapy: The most effective option for hot flashes and night sweats. If you have a uterus, progestin is needed to lower the risk of uterine cancer. This approach also helps prevent bone loss.
- Non-Hormonal Medications: SSRIs (such as paroxetine) and gabapentin can help with hot flashes, while fezolinetant (Veozah) can offer relief without hormones.
- Vaginal Estrogen: Available as creams, tablets, or rings, this treatment helps with vaginal dryness.
- Natural Remedies: Black cohosh, maca root, red clover, omega-3s, magnesium, and vitamin D may ease symptoms.
- Lifestyle Changes: Strength training, aerobic exercise, a balanced diet, good sleep habits, and stress management can improve well-being.
- Alternative Medicine: Bioidentical hormones, acupuncture, Ayurveda, and homeopathy may help but should be used with medical guidance.
- Weight & Metabolism: As estrogen levels drop, fat storage shifts and metabolism slows. Eating more protein and fiber, along with regular strength training and aerobic exercise, can help manage weight.
- Fatigue Management: B vitamins, iron, magnesium, vitamin D, and adaptogens like ashwagandha and rhodiola can support energy and focus.

The Most Effective Perimenopause Treatment Option
Medical Perimenopause Treatments: Hormone Therapy, SSRIs, and Gabapentin
Hormone therapy is the most effective way to manage hot flashes and night sweats. Estrogen therapy is available in various forms, including pills, patches, sprays, gels, and creams. Those with a uterus need to take progestin alongside estrogen to reduce the risk of uterine cancer. Additionally, hormone therapy helps prevent bone loss, lowering the risk of osteoporosis.
For those unable or unwilling to take estrogen, selective serotonin reuptake inhibitors (SSRIs) like paroxetine can ease hot flashes. Though typically prescribed for depression, these medications can help even without mood-related concerns.
Gabapentin, originally developed for seizures, has also been shown to reduce hot flashes. It may be particularly helpful for women who experience both migraine and menopause symptoms.
For more details, visit treatment options to help manage menopause symptoms.
Non-Hormonal Medications: Fezolinetant and Other Alternatives
Fezolinetant (Veozah) is a newer non-hormonal option that addresses moderate to severe hot flashes. It directly affects the brain’s temperature regulation, distinguishing it from hormone therapy. This treatment may be ideal for those who cannot use estrogen.
Other options include clonidine, which is commonly prescribed for high blood pressure, and low-dose antidepressants. Though they may not be as effective as estrogen, these medications can still provide symptom relief.
To read more about these treatments, visit the Mayo Clinic’s guide on perimenopause.
Vaginal Estrogen and Localized Perimenopause Treatment
For many, vaginal dryness and discomfort during intercourse are common in perimenopause. Vaginal estrogen therapy, available as creams, tablets, or rings, provides targeted relief. Unlike systemic estrogen therapy, this treatment stays localized, reducing the risks associated with full-body hormone therapy.
Regular use of vaginal moisturizers and lubricants can also help. Water- and silicone-based lubricants improve comfort during sex without affecting hormone levels.
There are multiple ways to manage perimenopause symptoms safely and effectively, whether through hormone therapy, non-hormonal medications, or localized treatments.
The Best Natural Perimenopause Treatment
Many people seek relief from perimenopause symptoms without hormones. Natural remedies, including herbs, supplements, and alternative therapies, may help ease discomfort.
Herbal Remedies
Certain plants contain compounds that influence hormone balance. Black cohosh may reduce hot flashes, though research results vary. Evening primrose oil is commonly used to alleviate hot flashes and breast tenderness. Ashwagandha is renowned for its ability to reduce stress and improve overall well-being. Be sure to consult with a healthcare provider before incorporating it into your routine.
Dietary Supplements
Several nutrients support hormone health. Omega-3s, found in fish oil, reduce inflammation and support brain function. Magnesium promotes better sleep, muscle relaxation, and stress management. Vitamin D is essential for bone health, but many people do not get enough. A doctor can check levels and recommend the right dosage.
Alternative Therapies
Acupuncture may improve blood flow, reduce stress, and help with sleep problems. Some report fewer hot flashes, though research is ongoing. Homeopathic approaches use small doses of natural substances to manage symptoms. These treatments are not FDA-approved, and results differ from person to person.
Combining herbal supplements, essential nutrients, and alternative approaches may provide relief. Tracking symptoms and discussing treatment options with a doctor can help identify what works best. Find more information on ways to relieve menopause symptoms. Additional resources can be found at the National Center for Complementary and Integrative Health.
Improving Hormonal Imbalance with Lifestyle Changes
Small adjustments to daily habits are a core perimenopause treatment for regulating and managing symptoms. Regular exercise, a balanced diet, and better sleep also contribute to hormonal stability.
Exercise Routines: Strength Training and Aerobic Benefits
Physical activity plays a major role in symptom management. Strength training, such as weightlifting or resistance band work, helps maintain muscle mass and bone strength, lowering the risk of osteoporosis. Aim for two to three sessions per week.
Aerobic exercise, including walking, swimming, and cycling, supports cardiovascular health and hormone balance. These activities also aid in weight management, which can become more difficult due to metabolic changes. A daily 30-minute workout can improve energy and mood.
Nutritional Adjustments: Balancing Estrogen with Diet
Diet impacts hormone levels. A well-rounded plan that includes fruits, vegetables, whole grains, and healthy fats may help. Foods rich in phytoestrogens, such as flaxseeds, soy, and chickpeas, can offer symptom relief.
Getting enough calcium and vitamin D supports bone health as estrogen levels decline. Dairy, leafy greens, and fortified plant-based milks are good sources. Reducing alcohol and caffeine may also help, as both can worsen hot flashes and disrupt sleep patterns.
Sleep Hygiene and Stress Management for Hormonal Health
Hormonal changes can cause sleep disturbances. Sticking to a bedtime routine and ensuring the sleep space is dark, cool, and quiet can improve rest. Reducing screen time before bed may also be beneficial.
High stress increases cortisol, which can disrupt hormone balance further. Relaxation techniques such as yoga, meditation, or deep breathing exercises may help.
Lifestyle adjustments will not eliminate all symptoms, but they can improve well-being. Explore more about perimenopause and how to adjust to its changes. Find additional expert advice at Women’s Health.
Alternative Medicine Options for Perimenopause Treatment
Many turn to alternative treatments for symptom relief. These include bioidentical hormone therapy, traditional Eastern practices, and homeopathic approaches.
Bioidentical Hormone Therapy: Benefits and Risks
Bioidentical hormones are chemically identical to the body’s natural hormones and come from plant sources like soy and yams. Some prefer this option over conventional hormone therapy.
This treatment can ease symptoms like hot flashes, night sweats, and mood swings. However, when prepared as compounded formulations, they are not FDA-approved, which raises concerns about consistency and safety. Misuse can lead to risks like blood clots or increased cancer risk. Consulting a doctor is important before starting this therapy.
Bioidentical Hormone Therapy: Benefits and Risks
Bioidentical hormones are chemically identical to the body’s natural hormones and come from plant sources like soy and yams. Some prefer this option over conventional hormone therapy.
This treatment can ease symptoms like hot flashes, night sweats, and mood swings. However, when prepared as compounded formulations, they are not FDA-approved, which raises concerns about consistency and safety. Misuse can lead to risks like blood clots or increased cancer risk. Consulting a doctor is important before starting this therapy.
Hormone Replacement Therapy (HRT): A Comprehensive Solution
Hormone Replacement Therapy (HRT) is a highly effective treatment for managing perimenopause symptoms such as hot flashes, night sweats, vaginal dryness, mood swings, and sleep disturbances. The primary goal of HRT is to replenish hormone levels that naturally decline during perimenopause.
Types of HRT
- Estrogen-Only Therapy: Suitable for women who have had a hysterectomy.
- Combined Estrogen-Progestin Therapy: Necessary for women with an intact uterus to reduce the risk of endometrial cancer.
- Low-Dose Vaginal Products: These include creams, tablets, or rings that primarily address vaginal symptoms without significantly affecting overall estrogen levels.
Benefits of HRT
- Symptom Relief: Alleviates common perimenopausal symptoms such as hot flashes and night sweats.
- Bone Health: Helps prevent bone loss and reduces the risk of osteoporosis-related fractures.
- Heart Health: May lower the risk of heart disease when started around menopause onset.
Risks Associated with HRT
While HRT offers significant benefits, it also comes with potential risks that should be carefully weighed:
- Breast Cancer Risk: Combined estrogen-progestin therapy may slightly increase breast cancer risk if used long-term.
- Blood Clots & Stroke: There is an elevated risk of blood clots and stroke associated with systemic hormone therapy.
- Gallbladder Disease: An increased incidence of gallbladder problems has been noted in some users.
It’s crucial to discuss these risks with your healthcare provider to determine if HRT is right for you based on your medical history and individual health needs.
For more detailed information on Hormone Optimization at The Woman’s Clinic in Little Rock, visit our Hormone Optimization page.
Find Relief with Perimenopause Treatment
Hormonal changes during perimenopause can cause symptoms like hot flashes, mood swings, and sleep disturbances—but you don’t have to navigate this transition alone. At The Woman’s Clinic in Little Rock, we offer personalized perimenopause treatment options to help you feel your best. Contact us today to explore solutions tailored to your needs.